Wednesday, May 5, 2010

Investigation#2: Anti IgE and IgE-producing B cell - Week 11 (Mar 26, 2010)

The author reflects on the findings of the study by Kerzel and colleagues which investigates the effects of altered antibody repertoire on the outcomes of allergic asthma. He notes that the results of the study indicate the significant role of anti-immunoglobulin E (IgE) and IgE-producing B cells in the perpetuation of allergic inflammation. He contends that with this research, new opportunities for other treatment approaches may become apparent

I am curious about allergy response related to IgE. I actually could not fully understand about this primary research article but I can see that the relationship between anti-IgE and B-cell could make alternate medication for allergic asthma.

Citation: Davies, J. M.. Altered immunoglobulin E diversity and regulation of allergic inflammation in asthma. Clinical & Experimental Allergy, Apr2009, Vol. 39 Issue 4, p455-457

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